What is Thymosin Alpha-1 (Tα1)?
Thymosin Alpha-1 (Tα1) is a 28-amino-acid peptide first isolated from thymic tissue, carrying an N-terminal acetyl group. It is distinct from Thymosin Beta-4 (TB-500) despite the shared family name. It is supplied as a lyophilized powder for in-vitro laboratory research use only.
Thymosin Alpha-1 research
Published work on Thymosin Alpha-1 is qualitative in the framing below. Each item describes the focus of the research itself, not an outcome for any person.
- Innate immune signaling. Research has examined Thymosin Alpha-1 in Toll-like receptor and dendritic-cell signaling models.
- T-cell maturation research. Studies have explored T-cell differentiation and maturation endpoints in cell and animal models.
- Infection-model research. Thymosin Alpha-1 has been the subject of studies in viral and fungal infection models.
- Immuno-oncology research. Investigations have examined its role alongside other agents in oncology research models.
Thymosin Alpha-1 specifications
| CAS Number | 62304-98-7 |
|---|---|
| Synonyms | Tα1, thymalfasin, thymosin α1 |
| Molecular Formula | Provided on batch COA |
| Molecular Weight | Provided on batch COA |
| Sequence | 28 amino acids, N-acetylated (provided on batch COA) |
| Purity | ≥99% by HPLC |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in bacteriostatic or sterile water |
| Storage | Store lyophilized at -20°C; protect from light |
| Shelf Life | 24+ months lyophilized at -20°C |
| Presentation | 10 mg per vial |
Thymosin Alpha-1 reconstitution & storage
Store the sealed lyophilized vial at -20°C. Reconstitute with bacteriostatic or sterile water by directing the stream against the vial wall; do not shake. After reconstitution, store refrigerated at 2 to 8°C and use within the period indicated on the batch COA. For laboratory research handling only.
Thymosin Alpha-1 certificate of analysis (COA)
A batch-specific Certificate of Analysis accompanies every order, as it does for all research peptides with published lab results from PeptideX1. The COA documents identity and purity by HPLC for the lot you receive, along with the molecular data listed as provided on batch COA above. Third-party analytical reports are available on request.
Thymosin Alpha-1 research references
- Goldstein AL, Low TL, McAdoo M, et al. Thymosin alpha1: isolation and sequence analysis of an immunologically active thymic polypeptide. Proceedings of the National Academy of Sciences. 1977. PubMed
- Romani L, Bistoni F, Montagnoli C, et al. Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance. Annals of the New York Academy of Sciences. 2007. PubMed
- PubChem compound record for Thymosin alpha-1. National Library of Medicine. PubChem
Thymosin Alpha-1 FAQ
What is Thymosin Alpha-1 (Tα1)?
Thymosin Alpha-1 (Tα1) is a 28-amino-acid peptide first isolated from thymic tissue, carrying an N-terminal acetyl group. It is distinct from Thymosin Beta-4 (TB-500) despite the shared family name. It is supplied as a lyophilized powder for in-vitro laboratory research use only.
What purity does PeptideX1 Thymosin Alpha-1 meet?
Each batch is ≥99% purity by HPLC, verified per batch on the accompanying Certificate of Analysis.
Is a Certificate of Analysis included?
Yes. A batch-specific Certificate of Analysis is included with every order.
How is it shipped and stored?
It ships lyophilized, sealed and desiccated. Store the sealed vial at -20°C and protect it from light.
How does Thymosin Alpha-1 differ from TB-500 (Thymosin Beta-4)?
They are different peptides from different thymosin families. Thymosin Alpha-1 is a 28-amino-acid acetylated peptide studied in immune-signaling research. Thymosin Beta-4 is a 43-amino-acid actin-binding protein, and TB-500 is a fragment of it. Both are supplied strictly as research materials.
Is this product for human use?
No. It is sold strictly for in-vitro laboratory research use only. It is not for human or veterinary use.